TargetToll-like receptor 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataKi: 11nMAssay Description:Displacement of Eu-DTPA from human TLR2 expressed in HEK293 cells after 1 hrMore data for this Ligand-Target Pair
TargetToll-like receptor 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataKi: 16nMAssay Description:Negative log concentration of antagonist was determined on 5-hydroxytryptamine 2B receptor of Rat stomach fundusMore data for this Ligand-Target Pair
TargetToll-like receptor 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataKi: 22nMAssay Description:Negative log concentration of antagonist was determined on 5-hydroxytryptamine 2B receptor of Rat stomach fundusMore data for this Ligand-Target Pair
TargetToll-like receptor 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataKi: 25nMAssay Description:Displacement of Eu-DTPA from human TLR2 expressed in SU.86.86 cells after 1 hrMore data for this Ligand-Target Pair
TargetToll-like receptor 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataKi: 25nMAssay Description:Displacement of Eu-DTPA from human TLR2 expressed in HEK293 cells after 1 hrMore data for this Ligand-Target Pair
TargetToll-like receptor 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataKi: 67nMAssay Description:Displacement of Eu-DTPA from human TLR2 expressed in SU.86.86 cells after 1 hrMore data for this Ligand-Target Pair
TargetToll-like receptor 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataKi: 91nMAssay Description:Displacement of Eu-DTPA from human TLR2 expressed in SU.86.86 cells after 1 hrMore data for this Ligand-Target Pair
TargetToll-like receptor 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataKi: 91nMAssay Description:Negative log concentration of antagonistic compound was determined on 5-hydroxytryptamine 2B receptor of Rat stomach fundusMore data for this Ligand-Target Pair
TargetToll-like receptor 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 48nMAssay Description:Inhibition of human TLR2 expressed in HEK-Blue-4 cells assessed as induction of NFkappaB by SEAP assayMore data for this Ligand-Target Pair
TargetToll-like receptor 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Antagonist activity at human TLR2 expressed in HEK-Blue cells assessed as inhibition of Pam3CSK4-induced TLR2/TLR1 activation by measuring decrease i...More data for this Ligand-Target Pair
TargetToll-like receptor 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Antagonist activity at human TLR2 expressed in HEK-Blue cells assessed as inhibition of Pam3CSK4-induced TLR2/TLR1 activation by measuring decrease i...More data for this Ligand-Target Pair
TargetToll-like receptor 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 230nMAssay Description:Antagonist activity at human TLR2 expressed in HE293 cells cotransfected with pELAM by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetToll-like receptor 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 240nMAssay Description:Antagonist activity at human TLR2 expressed in HE293 cells cotransfected with pELAM by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetToll-like receptor 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Antagonist activity at human TLR2 expressed in HEK-Blue cells assessed as inhibition of Pam3CSK4-induced TLR2/TLR1 activation by measuring decrease i...More data for this Ligand-Target Pair
Affinity DataIC50: 349nMAssay Description:Inhibition of biotin labelled Pam2CSK4 binding to mouse TLR2 Fc chimera protein after 45 mins by AlphaScreen assayMore data for this Ligand-Target Pair
TargetToll-like receptor 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 350nMAssay Description:Antagonist activity at human TLR2 in HEK-Blue hTLR2 cells assessed as inhibition of Pam3CSK4-induced receptor activation preincubated with Pam3CSK4 f...More data for this Ligand-Target Pair
TargetToll-like receptor 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 361nMAssay Description:Antagonistic activity against Bradykinin receptor B1 of rat ileum longitudinal smooth muscle.More data for this Ligand-Target Pair
TargetToll-like receptor 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Ligand Info
TargetToll-like receptor 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 426nMAssay Description:Inhibition of biotin labelled Pam2CSK4 binding to His tagged human TLR2 after 45 mins by AlphaScreen assayMore data for this Ligand-Target Pair
TargetToll-like receptor 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 460nMAssay Description:Antagonist activity at human TLR2 expressed in HE293 cells cotransfected with pELAM by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetToll-like receptor 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Ligand Info
TargetToll-like receptor 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 520nMAssay Description:Antagonist activity at human TLR2 in HEK-Blue hTLR2 cells assessed as inhibition of Pam3CSK4-induced receptor activation preincubated with Pam3CSK4 f...More data for this Ligand-Target Pair
Affinity DataIC50: 580nMAssay Description:Inhibition of Pam3CSK4-induced TLR1/TLR2 activation in mouse RAW 264.7 cells assessed as reduction in NO production incubated for 24 hrs by 2,3-diami...More data for this Ligand-Target Pair
TargetToll-like receptor 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Ligand Info
TargetToll-like receptor 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Ligand Info
TargetToll-like receptor 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Ligand Info
TargetToll-like receptor 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Ligand Info
TargetToll-like receptor 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Ligand Info
TargetToll-like receptor 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Ligand Info
TargetToll-like receptor 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 900nMAssay Description:Antagonistic potency at TLR2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetToll-like receptor 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 900nMAssay Description:Antagonist activity at human TLR2 expressed in HE293 cells cotransfected with pELAM by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetToll-like receptor 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Ligand Info
TargetToll-like receptor 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Ligand Info
TargetToll-like receptor 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 950nMAssay Description:Antagonistic potency at TLR2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetToll-like receptor 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Ligand Info
TargetToll-like receptor 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Ligand Info
TargetToll-like receptor 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Ligand Info
Affinity DataIC50: 1.04E+3nMAssay Description:Inhibition of biotin labelled Pam2CSK4 binding to mouse TLR2 Fc chimera protein after 45 mins by AlphaScreen assayMore data for this Ligand-Target Pair
TargetToll-like receptor 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.10E+3nMAssay Description:Antagonist activity at human TLR2 in HEK-Blue hTLR2 cells assessed as inhibition of Pam3CSK4-induced receptor activation preincubated with Pam3CSK4 f...More data for this Ligand-Target Pair
TargetToll-like receptor 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.10E+3nMAssay Description:Antagonist activity at human TLR2 in HEK-Blue hTLR2 cells assessed as inhibition of Pam3CSK4-induced receptor activation preincubated with Pam3CSK4 f...More data for this Ligand-Target Pair
TargetToll-like receptor 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Ligand Info
TargetToll-like receptor 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Ligand Info
TargetToll-like receptor 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Ligand Info
TargetToll-like receptor 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Ligand Info
TargetToll-like receptor 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human TLR2 expressed in HEK-Blue-4 cells assessed as induction of NFkappaB by SEAP assayMore data for this Ligand-Target Pair
TargetToll-like receptor 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.25E+3nMAssay Description:Antagonistic potency at TLR2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetToll-like receptor 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Ligand Info
Affinity DataIC50: 1.38E+3nMAssay Description:Inhibition of biotin labelled Pam2CSK4 binding to mouse TLR2 Fc chimera protein after 45 mins by AlphaScreen assayMore data for this Ligand-Target Pair
TargetToll-like receptor 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Ligand Info
TargetToll-like receptor 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Ligand Info